The kidneys are responsible for making a hormone called erythropoetin, which tells your body to make red blood cells. Red blood cells carry oxygen from your lungs to the rest of your body. As the kidneys fail, they make less erythropoetin and low levels of red blood cells (called anemia) results.
Fatigue / Weakness
With less oxygen going to your brain and muscles, you can become tired very quickly. Fatigue is the most common symptom of anemia but it can be caused by a lot of conditions unrelated to the kidneys as well.
Shortness of Breath
Shortness of breath from anemia is usually less severe than that cause by fluid overload. This type is usually noticeable when exerting oneself and not when at rest or lying on your back.
Feeling Cold
Many people with anemia are intolerant to coldness. They feel cold, even in a warm room. This is not specific to anemia or kidney disease and can be seen with thyroid disease or without any disease at all.
Impaired Thinking
The brain requires a lot of oxygen to function properly. Anemia can lead to difficulty thinking and concentration. Although not specific to anemia, it is often improved with treatment.
